OxyR Regulon Controls Lipid Peroxidation-mediated Oxidative Stress in Escherichia coli
نویسندگان
چکیده
منابع مشابه
OxyR regulon controls lipid peroxidation-mediated oxidative stress in Escherichia coli.
Membrane lipid peroxidation processes yield products that may react with DNA and proteins to cause oxidative modifications. The oxyR gene product regulates the expression of enzymes and proteins that are needed for cellular protection against oxidative stress. Upon exposure to tert-butylhydroperoxide (t-BOOH) and 2,2'-azobis (2-amidinopropane) hydrochloride (AAPH), which induce lipid peroxidati...
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متن کاملIn vivo transcription of the Escherichia coli oxyR regulon as a function of growth phase and in response to oxidative stress.
Simultaneous expression of seven genes in Escherichia coli was measured by a reverse transcription-multiplex PCR fluorescence procedure. Genes studied were (i) oxyR (transcriptional regulator); (ii) katG, dps, gorA, and ahpCF (controlled by OxyR); (iii) sodA (controlled by SoxRS); and (iv) trxA (not related to OxyR or SoxRS). Except for trxA, transcription of all genes was activated during the ...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2002
ISSN: 1976-6696
DOI: 10.5483/bmbrep.2002.35.3.297